Biosafety assessment of Ficus carica Leaf in rat; an alternative preservative agent

  • Olufemi Emmanuel Bankefa ORCID Mail Federal University Oye-Ekiti, Department of Microbiology, Ekiti State, P.M.B. 363, Nigeria
  • Ruth Adefolakemi Gabriel-Ajobiewe Department of Microbiology, Federal University Oye-Ekiti, Ekiti-State, Nigeria
  • Seye Julius Oladeji ORCID Department of Microbiology, Federal University Oye-Ekiti, Ekiti-State, Nigeria
  • Gbenga Victor Kayejo Department of Microbiology, Federal University Oye-Ekiti, Ekiti-State, Nigeria
Keywords:
Biosafety assessment, Ficus carica, Preservative, leaf extract, haematological parameters, histological changes

Abstract

Due to the global disturbance of chemical resurgence in food efforts, Ficus carica leaves had been made to be applied as preservatives to extend the shelf life of perishable foods despite limited information regarding its biosafety. Hence, the need to affirm the safety of this plant in-vivo was studied. Extracts of Ficus carica leaf were mixed with the basal diet of Wistar albino rats and used as feed for one group of Wistar albino rats (treated group) while the second group was fed with sole basal medium to serve as a control. The blood samples of both groups were taken before the rats were subjected to cervical dislocation. Hematological and histological parameters were studied to know the effects of the extracts and in order to justify the usage of plant extracts as preservatives for perishable foods. The hematological parameters of the treated rats were considerably higher than that of the control rats except for the insignificant changes in lymphocytes, basophils and eosinophils. Furthermore, the histological study revealed no sign of lesions in all organs examined from both groups. The adoption of F. carica leaf as preservatives has no contraindication on the organs or blood parameters which thus necessitate that global application should be recommended not only on perishable foods since its resurgence will pose no harm to the consumers.

Author Biographies

Olufemi Emmanuel Bankefa, Federal University Oye-Ekiti, Department of Microbiology, Ekiti State, P.M.B. 363, Nigeria
Department: Microbiology Rank: Lecturer II (PhD)
Ruth Adefolakemi Gabriel-Ajobiewe, Department of Microbiology, Federal University Oye-Ekiti, Ekiti-State, Nigeria
Department: Microbiology Rank: Associate Professor (Reader)
Published
2020-10-07
How to Cite
1.
Bankefa O, Gabriel-Ajobiewe R, Oladeji S, Kayejo G. Biosafety assessment of Ficus carica Leaf in rat; an alternative preservative agent. J Food Safe & Hyg. 5(3).
Section
Original Article(s)