Tehran University of Medical Sciences Journal of Food Safety and Hygiene 2476-3241 7 2 2022 01 13 68 76 Marzyieh Karami Division of Food Safety and Hygiene, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Mahsa Alikord Tehran University of Medical Sciences, Zahra Mokhtari TUMS Parisa Sadighara Division of Food Safety and Hygiene, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Gholamreza Jahed-Khaniki Division of Food Safety and Hygiene, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2021 06 10 2021 07 25 Sodium hydrosulfite is called blankit with the chemical formula Na2S2O4 is a toxic food additive employed in the food industry to improve the apparent quality of food. Adverse effects of blankit include the elimination and damage of villi in the stomach and intestines in the long term, therefore, it can cause the development of gastrointestinal cancer. It is also known to be an effective factor in causing diabetes. In this study, based on searches in PubMed, Google Scholar, Elsevier, SID databases and keywords studies on the use of sodium hydrosulfite and its health effects were reviewed from 2008 to 2018 According to the results of studies conducted, it was found that the amount of this substance is used more than the maximum allowed in some food, which requires more monitoring of the quality of food produced. https://jfsh.tums.ac.ir/index.php/jfsh/article/view/308 https://jfsh.tums.ac.ir/index.php/jfsh/article/download/308/164